The pharmaceutical industry faces a significant challenge: about 90% of oral drugs in development are practically insoluble in the gastrointestinal tract, leading to poor absorption and reduced efficacy. As a result, formulating these drugs can be a challenge. Suboptimal formulations can lead to high pill burden, gut irritation and associated side effects. Ultimately, they may fail to achieve the necessary drug blood concentrations for a clinical benefit.

At Tret Therapeutics we have developed a proprietary oral formulation technology that results in highly bioavailable dosage forms of most poorly water soluble drugs. Thus we can minimize dose and side effects while maximizing therapeutic effect.

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Learn more about our approach.